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Efficacy and Safety of Rituximab in Central Nervous System Demyelinating Disorders (Indian context)

Efficacy and Safety of Rituximab in Central Nervous System Demyelinating Disorders (Indian context)

Journal: Annals of Indian Academy of Neurology; January 11, 2022

Author(s): Varsha A Patil, Saurabh N Kamat, Jamshed A Lalkak and Bhim Singhal

Effectiveness and safety of rituximab in MS, NMOSD, and MOGAD

In this retrospective study of 61 MS, 37 NMOSD, and 4 MOGAD patients in India, rituximab treatment eliminated relapses in 97% of MS, 67% of NMOSD, and 50% of MOGAD patients over the study duration of June 2008 to January 2020. The disability scores improved in some MS patients but remained constant in NMOSD and MOGAD patients. The study concluded that rituximab is effective and safe in Indian patients with MS and NMOSD.

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